so a few of my friends have told me to add 6oz of acetone per 10gal of gas will improve the overall mpg and a small boost in performance?? is this true? and are there any neg ramifications?

There's plenty to read about this topic on the Web.
Here's one of the many sites. http://www.lubedev.com/smartgas/additive.htm

Myself, I have no experience of using it.